Ensure you have a REQUIRED link to comprofiler (as instructed in documents and readme.txt). Not userlist, not registration, etc.. to comprofiler as in www.yoursite.com/index.php?option=comprofiler. This can be created as a menu type when adding a menu link (don't use external link).
Next disable all SEO and cache (purge cache after disabling) and see if issue persists.
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