Hello,
I had this problems back !
But now, my left menu was lost after a clic on a profile, to get details: just after selecting it tru a list member !
So, I've been to SH404Sef components config, selecting "no cache" on comprofiler, clean, and back to "normal treatment"...Then it works !
Without SH404Sef ( but SEF activated into Joomla! config) I don't have any problems...
J! 1.5.10 / CB 1.2.1 (1.2 as well)