I have already posted elsewhere about this but I think it's so important it should be core CB.
As a team manager (gamers clan site) I specifically need CB to Block anyone else but the team members. I have SMF to manage other peoples profiles, I use CB to manage the team.
Other sites like Sport clubs etc will need something similar but allowing basic profile options as well. (ie groups)
I know of Music sites that use CB to display Band pages like user pages and only bands due to the plug ins use being optional. (ahh again another user list to edit...)
It would be a blessing for me to at least go into the user manager and remove the 120 + names from CB (functionality) so I can allow the team to create better profiles with more fields running automatically..